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Corresponding fatty acid analyses revealed large shifts in the composition of the bkd strain depending on the supplied precursor (Fig 1B and Appendix Fig S1B)

Studies show core biological changes, including reduced NK cell function, activation of the NLRP3 inflammasome, altered interferon and cytokine signaling, and evidence of mitochondrial and metabolic dysfunction (lactate/pyruvate, haptoglobin)

CBT-I focuses on breaking the cycle of racing thoughts, nighttime anxiety, and poor sleep routines

The interactions are weakened by the presence of unsaturated fatty acids