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Phase I metabolism of dihexa, which was determined using pooled male rat liver microsomes, was found to be veiy low with an average intrinsic clearance (Clin t ) of 2.72 7/ and an average half-life of 509.4 minutes

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Synergy and antagonism in natural product extracts: When 1 + 1 does not equal 2

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Unlike dopaminergic or GABAergic compounds that cause receptor downregulation, c-Met receptor density doesn't decrease with prolonged agonist exposure in published models