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Many of these biomarkers emerged from pre-clinical studies

[DOI] [PubMed] [Google Scholar] 283.Pereda, J

Endogenous interleukin 18 suppresses hyperglycemia and hyperinsulinemia during the acute phase of endotoxemia in mice

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This dual capacity for efficacy and safety screening establishes the zebrafish not merely as a tool, but as a highly efficient and cost-effective integrative platform for the early-stage discovery and evaluation of plant-derived hepatoprotective agents (Shimizu et al., 2023)
