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Napolitano G, Fasciolo G, Di Meo S, Venditti P, Vitamin E

Autopsy reports on AD patients indicate that there is a significant decrease in the proportion of normal mitochondria and a marked increase in the proportion of fractured cristae in their neurons compared to those of controls (Hirai et al., 2001)

(5) Yu-Xiang Kong, Zhi-Shuai Li, Yuan-Bo Liu, Bo Pan, et al (2025) FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation Communications Biology, volume 8, Article number: 299 (2025)

AS catalyzes the formation of argininosuccinate from citrulline and aspartate and is degraded in the liver during liver injury and released into the circulation
n = 4 mice for each genotype
