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B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) levels may be elevated as a result of increased right ventricular wall stress resulting from PH, but they may also be elevated in left heart failure without PH

3.2.3 Sex hormones abnormalities Many research has discovered sex differences in the prevalence of both GD and depression, with a reported male-to-female ratio of 1:4-6 in GD and a ratio of roughly 1:2 in major depressive disorder (122, 128, 129)

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Ullman et al., 1996)

Think of it like the mild soreness you feel after a good workoutits a signal that your body is getting to work and rebuilding