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Lyophilized peptides lack the aqueous environment required for rapid hydrolysis, making them far more forgiving during accidental temperature excursions

or i.g., without adverse effects was shown in mice, and a lethal dose (LD1) was not achieved, which also shows metabolites without harmful effect [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]

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In contrast, GPx-1-overexpressing mice are partially protected from dopaminergic damage in response to 6-hydroxydopamine-induced toxicity (29)