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1 Introduction Hepatocellular carcinoma (HCC) is the most frequent malignant tumor of the liver, with the highest occurrence among people with chronic liver disease (1) and a dismal 5-year survival rate

GCL-catalyzed conjugation of the -carbonyl group of glutamate with the amino moiety of cysteine is the rate-limiting step in glutathione synthesis

The shuttling of the beta-oxidation intermediates may occur at physical contacts between the two organelles 162 or potentially via as of yet uncharacterized bi-directional vesicular trafficking 163 , likely involving carnitine acetyl transferases 164

TP53 mutations in human cancers: origins, consequences, and clinical use

Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: A cross-sectional analysis in the EPIC-Oxford cohort