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Homocysteine and lipids: S-Adenosyl methionine as a key intermediate

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In the liver, the accumulation of lipids is thought to impair mitochondrial function, thus reducing fatty acid oxidation and increasing the production of reactive oxygen species (ROS) that trigger lipid peroxidation, DNA damage, and apoptosis

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The prognosis for MNTI is generally good with a postoperative recurrence rate of approximately 1545% mostly due to incomplete resection of the primary lesion ( in situ despite the choice to expand the surgical resection area, which increased the tissue trauma to the child
