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Garca-Ruiz C, Fernndez-Checa JC (2018) Mitochondrial oxidative stress and antioxidants balance in fatty liver disease

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Furthermore, the population of cancer stem cells (CSCs) within any tumor (now widely accepted to be the major source of resistance to conventional therapies), exhibits more pronounced iron dependency based on import and storage capacities compared to non-stem cancer cells [2, 3]

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Molecules like the cell cycle protein p21 have been reported to interact directly with GPX4, competitively or allosterically affecting its ubiquitination rate, thereby stabilizing GPX4 and enhancing cellular resistance under oxidative stress (Zheng et al., 2024)

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[DOI] [PubMed] [Google Scholar] 56.Murry C.E., Soonpaa M.H., Reinecke H., Nakajima H., Nakajima H.O., Rubart M., Pasumarthi K.B.S., Virag J.I., Bartelmez S.H., Poppa V., et al

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