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Ethanol-exposed rats subjected to CMS exhibit exaggerated corticosterone responses and glucocorticoid receptor (GR) resistance in the PFC and hippocampus, mimicking the HPA axis hyperactivity observed in depressed humans (Alhaddad et al

Crohns Colitis 8, 252253

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Further evidence also states that stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic agent, proven in clinical trials to be both safe in inflammatory bowel disease and wound healing, stable in human gastric juice, with no toxicity being reported [12]