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Description
While creatine is commonly associated with athletic performance benefits, our study specifically emphasizes its efficacy for LMNA (R453W) fish, and l-carnitines effectiveness for LMNA (L35P) fish aligns with our broader objective of personalized medicine tailored to different LMNA variants

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Funding This work was supported by the National Key R&D Program, Ministry of Science and Technology of China (2023YFC3603300, 2023YFF1001000), the National Natural Science Foundation of China (82471591, 82460283), the Start-up Fund for Doctoral Research at the Affiliated Hospital of Guizhou Medical University (gyfybsky-2022-38), Guizhou Province (Qiankehebasis-ZK [2024] general 241), the 2025 Annual Hospital-Level Scientific Research Fund of Guizhou Hospital of Beijing Jishuitan Hospital (JGYYK[2025]-24) and the Key Medical Discipline Construction Project of Guizhou Provincial Health Commission during 20252026

Most of these works are phase 1 and phase 2 trials conducted in the United States and Egypt

[DOI] [PubMed] [Google Scholar] 18.Long L.E., Chesworth R., Huang X.F., McGregor I.S., Arnold J.C., Karl T
