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75 The poor water solubility and poor absorption of curcumin, however, prevent its widespread use as an anticancer treatment and the bioavailability of curcumin remains incredibly low

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Recent transcriptomic studies further support this evidence: in Kenyan indigenous chickens from lowland (Mombasa) and highland (Naivasha) ecotypes, qRT-PCR validated the expression of HSPH1 , PDK4 , and SRGN [4], while in the L2 strain of Taiwan country chickens, acute heat stress significantly upregulated resilience-associated genes such as HSP70 , HSP90AA1, HSP25, BAG3 , and DNAJA4 [66]

Roy K, Kodama S, Suzuki K and Watanabe M