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furthermore, the in vitro migration and rate of spreading of tendon fibroblasts increased in a dose-dependent manner, which was attributed to the activation of the FAK-paxillin pathway

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[DOI] [PubMed] [Google Scholar] 55.Johnson K., McEvoy C.E., Naqvi S., Wendt C., Reilkoff R.A., Wetherbee E.E., Nelson D., Tirouvanziam R., Niewoehner D.E

This enhanced microvascular integrity fundamentally alters the local biological environment, ensuring an exponentially higher delivery rate of oxygen, growth factors, and critical nutrients to tissues that are notoriously avascular or poorly vascularized, such as dense tendons, ligaments, and deep cartilage matrices, thereby dramatically accelerating their biological repair timelines