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This factor is not complement, cytokine or immunoglobulin, and appears to be packaged into exosomes ( Taken together, the above observations suggest that B cells might play a key upstream role in MS pathogenesis, and quite unexpectedly, could be stimulated to upregulate machinery unrelated to their traditional immune functions (Lisak et al., 2012, 2017)

The protective effect acting on the cell is based on inhibiting oxidative stress, apoptosis, or functioning metabolism at the lowest possible energy level in case of deficiency

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She et al, 2016)

Mucociliary clearance timing The nasal cavity clears deposited material at a rate of approximately 5-6 mm per minute through mucociliary transport