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It is possible the human trials never delivered enough intact peptide to the relevant tissue to reproduce the rodent effect, though this remains a hypothesis rather than a demonstrated cause of failure
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Animals from the AMPT group received two intra-peritoneal injections of AMPT (25 mg/kg each), separated by 2 hours
For anyone whose primary concern is metabolic health beyond just weight loss, this liver data should heavily influence the dosage comparison decision
Handel et al
