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This would provide a more accurate depiction of the action of MET inhibitors in vivo, and subsequently their likely clinical benefit

This review focuses on one over looked neurotrophin, hepatocyte growth factor (HGF) that acts via the Type 1 tyrosine kinase receptor Met to mediate stem cell differentiation, synaptogenesis, neurogenesis, and protect against tissue insults in a wide range of cell types including neurons

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In conclusion, our findings emphasize the complexity of CMH pathogenesis and highlight the need for multi-targeted therapeutic approaches