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[DOI] [PMC free article] [PubMed] [Google Scholar] Park C

However, the therapeutic utility of doxorubicin is undermined by its dose-dependent cardiotoxicity, possibly arising as a result of futile redox cycling, with NADH dehydrogenase within the mitochondria proposed as the most likely site of anthracycline reduction 9,10

(2013) by applying this method in their investigation into distinguishing between various monoclonal antibody versions according to hydrophobicity

One of the reasons why some whitening soaps are unlabeled is because there are harmful ingredients added to it like steroids, mercury and hydroquinone

Antibodies with a preferential role in ADCs must have the following characteristics: special targeting ability to deliver cytotoxic drugs to the tumor cells, high affinity binding to tumor cell-surface antigens and the ability to induce the cells endocytosis, low immunogenicity and the appropriate linkage sites which would not impact the affinity, endocytosis or efficacy of cytotoxic drugs [32]