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Hyperglycemic state increases the production of di-lipoylglycerol (DAG) (Hayashi and Shirai, 2022), which is an endogenous activator of PKC

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This form has a shorter half-life of about 30 minutes , meaning it mimics the bodys natural pulsatile release of GHRH

Graphical abstract Similar content being viewed by others Introduction Certain medications are likely to cause cochlear and/or vestibular system cell degeneration, resulting in temporary or irreversible hearing loss, ataxia, tinnitus, dizziness, ear infections, nystagmus, vertigo hyperacusis, and other ear problems (Kim et al