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Description
Occludin, claudin-5, and claudin-8 were found to be downregulated and redistributed, whereas claudin-2 (pore-forming TJ protein) was strongly upregulated

2016 doi: 10.1038/nature19079

Hyaluronic Acid 1% - Deeply hydrates and plumps the skin using low- and medium-molecular weight molecules

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High insulin levels suppress IGF binding protein (BP)-1 resulting in a relative increase in free IGF-I levels
