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Licensed alternatives for weight management, including semaglutide (Wegovy) and liraglutide (Saxenda), are available through regulated NHS and private pathways following NICE appraisal

Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein

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