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These finding strongly suggested that these three RND efflux systems are actively responding to copper stresses in P
Additionally, mesenchymal stem cell-derived exosomes (MSC-Exo) were modified by Cui et al
Chaperones attempt to remedy the unfolded protein first and, if unsuccessful, activate cellular programs, including the UPR, heat shock response (HSR), and ER-associated degradation (ERAD), to induce processes to either fix the problem or destroy the unfolded proteins (324, 325)
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