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Beauty truly is an inside job

Science 293 , 16731677 (2001)

Two processes generate the hydroxyl radical

Heptanoate can be metabolized to propionyl-CoA, producing succinyl-CoA after carboxylation and thereby re-filling a key substrate of the tricarboxylic acid (TCA) cycle [167]

With the assistance of complexes, such as Drosha/DGCR, Exportin-5/RAN-GTP, and Dicer/TRBP, primary miRNAs (pri-miRNAs) transcribed from the non-coding region of miRNA genes are processed to form mature miRNAs (Fig
