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Description

Conversely, a chronic increase of ROS can either overwhelm the responsive capacity of these pathways or induce the oxidation of specific components of UPR, UPS, or autophagy, thus exacerbating the accumulation of unfolded/misfolded proteins (333, 334) (FIGURE 9)

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In patients with Parkinson's disease, the use of dopamine receptor agonists can cause sudden sleep.In such cases, it is recommended to reduce the dose of the drug Dostinex