vulvar labial melanotic macules macule (brown spot on lip) (Stony Brook Case 1) dermatology dermatopathology Mystery behind labial and oral
Description
It reacts with hemoproteins and Fe 2+ producing peroxyl and alcoxyl free radicals, which enter to the propagation phase of the lipid peroxidation radical chain reaction

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Conversely, leptin inhibits orexigenic Agouti-related peptide (AgRP)/neuropeptide Y (NPY) neurons, which antagonize MC4R signaling

They focus on fat cells that dont respond to diet and exercise, breaking them down without harming nearby tissues
