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Critical Reviews in Biochemistry and Molecular Biology

This is why some formulation scientists recommend slightly acidic buffer solutions for peptide storage when long-term stability is needed

The following databases were searched: Ovid MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, Ovid Embase, Wiley Cochrane, EBSCO Cumulative Index to Nursing & Allied Health Literature (CINAHL), and Centre for Reviews and Dissemination/International Agency for Health Technology Assessment

The formula is straightforward: Concentration (mg/mL) = Total mg in vial Total mL of BAC water added Dose volume (mL) = Target dose (mg) Concentration (mg/mL) The most common approach is adding 2 mL of BAC water, which produces easy-to-measure concentrations