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It is known that some chemicals which alter the genes involved in the HPT axis homeostasis may be associated with an increased incidence of thyroid dysfunction, such as hypothyroidism, hyperthyroidism and cancer (6972)

Serine Signaling Governs Metabolic Homeostasis and Health. Trends in Endocrinology and Metabolism 34: 361372

Eight male pups were subjected to social isolation stress and received normal saline

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Therefore, engineering for optimal engagement of the neonatal Fc receptor (FcRn) is crucial, as binding rescues IgG from intracellular degradation 14
