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Description
Sirtuins, including SIRT3, play a central role by deacetylating key proteins in the electron transport chain, cyclophilin D of the mitochondrial permeability transition pore (MPTP), and antioxidant enzymes such as superoxide dismutase 2 (SOD2) [36, 37]
A theoretical concern involves the potential role of thymosin beta-4 in tumor progression
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However, our knowledge of the functions of these cycles and their component enzymes continues to grow and evolve
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