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For others, it can cause physical discomfort, hygiene problems, rashes, skin infections, and difficulty exercising

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& Hadfield, J

The first treatment line is corticosteroids, and prednisolone, starting at 60 mg/day in adults, then tapered down

In addition, bile acids shape the composition of the gut microbiota and are transformed by gut bacteria, creating a feedback mechanism essential for liver and gut health (48)
