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Radioimmunoassay was used for measurement of insulin (Diagnostic Products, Los Angeles, CA)

Together with V103I (average odds ratio, 0.80), these two variants may provide 2% protection of obesity, similar to the roughly 2% cause of obesity by pathogenic loss-of-function mutations in the MC4R (457)
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[14] She later took gold at the 2012 Russian Junior Championships
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