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Overall, structural modifications, including the stapling motif ( i,i + 7), specific positioning of the staple, N- and C-terminal residues, conservation of leucine side chains, and preservation of charged/polar residues D146, E151, and N153 directed the improved potency and specificity of 1907 as a FAK scaffold inhibitor

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Defined 15-amino acid peptide , commonly referenced in preclinical literature as a stable gastric pentadecapeptide. Small 5 mg format suitable for research teams running pilot studies, method development, or multiple assay conditions

Amelioration of persistent left ventricular function impairment through increased plasma ascorbate levels following myocardial infarction