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These safety characterisation studies have established the pre-clinical basis for the well-tolerated profile of both peptides in rodent research models and havent identified significant toxicological findings at doses producing meaningful biological effects and contributing to their establishment as reference research compounds in pre-clinical regenerative biology

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Given the evidence linking gut dysbiosis with neurodegenerative disease mechanisms, a variety of strategies are being pursued to modulate the microbiotagutbrain axis for therapeutic benefit (Fig