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Such an increase in MDA-modified proteins, anti-SOD, and anti-catalase antibodies in SLE patients induces oxidative stress with the onset of the disease ( Interestingly, these ROS indicators of oxidative damage can be considered for the development of biomarkers ( 4 Armory of immune cells dysregulating SLE 4.1 Functional influence of T cells and B cells in SLE T cells play a major role in the initiation of SLE, and uncontrollably activated B cells are produced by T-cell dysregulation, which impacts peripheral immune tolerance

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doi: 10.1016/j.exer.2025.110601 185 WangYLiPWangCBaoSWangSZhangGet al

Blood 95 , 27762779 (2000)

doi: 10.3389/fsufs.2020.00136 31 EgamberdievaD.WirthS