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First, the nanoparticles associate with the cell membrane and subsequently are endocytosed
Akmal A, Javaid A, Hussain R, Kanwal A, Zubair M, Ashfaq UA

Clinical metabolomic studies in peritoneal dialysis patients further demonstrate increased PCS and TMAO alongside reduced SCFAs, supporting the concept of a toxin accumulationSCFA depletionbarrier dysfunctionsystemic inflammation cascade (50)

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The nuclei were stained at RT for 10 min without light by DAPI
