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Endothelial injury generated directly by intracellular viral replication and by ACE2 downregulation, exposing cells to angiotensin II in the absence of the modulator effects of angiotensin 17 (270, 271), and vascular chronic inflammation promoting the development of tissue macrophages overloaded by cholesterol (foam cells), both increase the possibility of acquiring a severe COVID-19 infection (170, 209, 258, 259, 272, 273)

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Grce son rle cl dans la protection des cellules et le maintien de lquilibre interne, il constitue un alli intressant pour ceux qui souhaitent soutenir leur vitalit et leur bien-tre gnral

J Neurosci 22:33063311 Kenny PJ (2011) Common cellular and molecular mechanisms in obesity and drug addiction

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