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This practice can make drugs of otherwise indispensably potent value more tolerable to certain patients and spare them needless suffering, hence-reducing the overall side-effect burden or concern thereof
Liu, J., Hua, J., Wang, Y., Guo, X
Sjblom R
Neurochem Int 61:649658 Mallorga PJ, Williams JB, Jacobson M, Marques R, Chaudhary A, Conn PJ, Pettibone DJ, Sur C (2003) Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4-fluorophenyl)-3-(4 phenylphenoxy) propyl]) sarcosine
10.1126/scitranslmed.aaz2841 97 RoslanF.KushairiA.CappuynsL.DaliyaP.AdiamahA
