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Alzheimers Dement 13(11):1187-96 2017 PMC590996 Howard BV, Aragaki AK, Tinker LF, Allison M, Hingle MD, Johnson KC, Manson JE, Shadyab AH, Shikany JM, Snetselaar LG, Thomson CA, Zaslavsky O, Prentice RL

While the treatment for pruritus stemming from cholestatic liver disorders is established, pruritus originating from non-cholestatic causes is frequently encountered in cirrhotic patients due to various non-cholestatic factors

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Pi3k/akt signaling activation by roflumilast ameliorates rotenone-induced parkinsons disease in rats

LC contributes in the oxidation of long-chain fatty acid in the brain, boosts acetylcholine production (acyl group donor), increases protein-43 expression, inhibits cell damage and neuronal damage, and boosts neurotransmission
