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Patients (and caregivers of patients) should be informed that AEDs increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of the signs and symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thought about self-harm

Huperzine A for Alzheimer's disease

The disease affects about 5 million Americans, mostly over age 40

doi:10.3390/ijns5030029 [2] National Institutes of Health

We then proceed with a stratified meta-analysis for study quality, trial size, concealment of allocation, blind adjudication of events, analysis according to the intention-to-treat principle, and intervention method