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Agraib LM, Yamani MI, Tayyem R, Abu-Sneineh AT, Rayyan YM

For CMS, the currently identified potential pathogenic mechanisms only show a negative correlation with CMS, lacking direct evidence of causality

4.3.1 Nrf2 Nuclear factor erythroid 2 (Nrf2), a protein that regulates genes involved in both ferroptosis and inflammatory pathways, represents a target in depression

Research into genetic variations in SOD genes also underscores their significance in CRC susceptibility and management, indicating that a deeper understanding of SODs roles may enhance therapeutic strategies [97]

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