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Unlike earlier compounds that affected multiple methyltransferases, 5-amino-1MQ demonstrates remarkable specificity for NNMT without inhibiting related SAM-dependent enzymes or components of the NAD+ salvage pathway

In these cases, serum B12 levels will shoot up (the blood test counts inactive B12 too), but there may still be a deficiency of adenosyl B12 and methyl B12 in the cells, tissues and body fluids

The study population comprised healthcare professionals, including doctors, medical students, nurses, and other support staff working at the participating hospitals

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