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In high-fat-diet-induced rat hyperlipidemia, lycopene restored the level of TJ molecule claudin-5, and decreased VEGF, vascular cell adhesion molecule-1 (VCAM-1) and proinflammatory cytokines [222]

Freeman, J

For example, a novel GSH formulation bypassing the gastrointestinal digestion through an oral absorption, gave positive results in raising GSH blood concentration in vitro and in vivo (31)

Paired box 6 (PAX6) is a DNA-binding transcription factor that downregulates the expression of the vascular endothelial growth factor A (VEGFA) gene in glioma cells to suppress tumor cell invasion

This process is exacerbated by smoking, pollution, exposure to UV or ionizing radiation, eating fried foods or those cooked at high temperatures, as well as engaging in high-intensity exercise (12)