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doi: 10.3389/fimmu.2024.1381272 81 MayborodaOALageveen-KammeijerGSMWuhrerMDolhainR

Diagnostics (Basel) 2020;10:419

Summing up, ACE2 would also have a role in modulating innate immunity and influencing the composition of the gut microbiota

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The regulatory mechanisms can be transporter and cell-type specific: phosphorylation of EAAT2/GLT1 stimulates glutamate transport whereas phosphorylation of EAAT1/GLAST inhibits it