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If APAP were being developed today, an early indication of this variability could be obtained from a knowledge of the cytochrome P450 (CYP) enzymes responsible for its metabolic activation and their population variability

GSH is increased when the body is exposed to oxidants and electrophiles and, when decreased, yields a vulnerable state for some diseases [22]

Dogs under higher physiologic demandolder dogs, dogs recovering from illness, or dogs with chronic inflammatory conditionsare often the ones owners think about first

The oral solution of NAC was approved by the FDA for the treatment of acetaminophen overdose in 1978

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