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BotelhoMARaoVSCarvalhoCBBezerra-FilhoJGFonsecaSGValeMLet al

Studies have suggested mechanisms regarding the interaction between the microbiota and the gut-brain axis

Through its deacetylase activity, the NAD + -dependent deacetylase sirtuin-1 (SIRT1) meticulously regulates a variety of substrates, such as histone and non-histone proteins, thereby producing significant effects on metabolic homeostasis, apoptosis regulation, inflammatory responses, attenuation of oxidative stress, and even the aging process (Tanno et al., 2007

Sharma GS, Bhattacharya R, Singh LR

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