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Description
HSP shows a high degree of homology among species from microbes to humans (Khandia et al., 2017)
Hirsch IB, Juneja R, Beals JM
Results Cryo-EM structure determination of OCTN2 To determine the structure of OCTN2, we overexpressed full-length human OCTN2 in HEK293F cells and isolated the transporter using a GFP-nanobody purification strategy 28
A comprehensive understanding of their roles in both compartments is essential for designing therapies that selectively induce ferroptosis in tumors while preserving or enhancing immune function ( Table 1 )
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