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have designed a MPP-modified Doxorubicin-loaded N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer conjugates to target mitochondria, aiming to address mitochondrial dysfunction and achieve anticancer effects

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This means very little of the active ingredient actually makes it to your cells

While in the vasculature, the RBP4-retinol complexes interact with the protein transthyretin which prevents loss of retinol via renal glomerular filtration

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