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Neurofibrillar tangle-bearing neurons have been shown to contain more intracellular free cholesterol than adjacent tangle-free neurons in human AD brains (Distl et al., 2001)

This is because of a pigment called urochrome

[DOI] [PubMed] [Google Scholar] 86.Hirrlinger J., Gutterer J.M., Kussmaul L., Hamprecht B., Dringen R

& Cao, Y
