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mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4

titled Glutathione Stimulates Vitamin D Regulatory and Glucose-Metabolism Genes, Lowers Oxidative Stress and Inflammation, and Increases 25 OHD Levels in Blood: A Novel Approach to Treat 25-Hydroxyvitamin D Deficiency clearly outlines this relationship and describes how increasing GSH has been shown to increase the bioavailability of 25(OH)D

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119 , where disruption of this enzyme in hepatocellular carcinoma killed cancer cells through the buildup of its substrate

doi: 10.1021/acs.jafc.3c07844 14