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10.18632/aging.204745 135 ZhouY.WangX.GuoS.LiR.LiY.YuY.et al (2024)

A attracts and activates microglia and astrocytes, leading to the release of pro-inflammatory mediators such as TNF, IL-6, IL-2, and IL-1, as well as reactive oxygen and nitrogen species produced by oxidative stress, which ultimately leads to neuronal cell death (35)

doi:10.1111/joim.13141

Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations

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