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TB-500 has also been shown to accelerate tissue repair and wound healing by upregulating actin, while blocking acting polymerization

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GHK-Cu works through copper delivery to metalloenzymes and broad gene expression modulation, affecting not only collagen synthesis but also collagen cross-linking (via lysyl oxidase), glycosaminoglycan production, anti-inflammatory pathways, and antioxidant defense systems

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FIGURE 1 GHK Ameliorated Inflammation and Metalloprotease/Anti-metalloprotease Imbalance in ICH To investigate the effect of GHK following ICH, we estimated the level of TNF- and IL-1 in ICH brain samples using ELISA (Figures 2A,B)