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They are sensitive and reliable (Norman & Morrison, 1993
However, this study was undertaken in 13 day old mice, as without IR they were not viable, and thus, results are not conclusive [159]
Key limitations include poorly characterized pharmacokinetics (rapid absorption but extensive metabolism and low systemic bioavailability for eugenol), variable extract standardization, heterogeneous assay methodologies, and limited in vivo and clinical data
Possible side effects of B12 + MIC shots include: Injection site reactions Mild pain, redness, or swelling at the injection site
